Cancer is one of the leading causes of death in dogs—especially as they age. While genetics can play a role, many veterinarians and researchers agree that diet, toxins, immune stress, and chronic inflammation strongly influence whether cancer develops and how aggressively it progresses.
I’ve lost two dogs to cancer (hemangiosarcoma and lymphoma). The veterinarian suspects Rodrigo had also developed hemangiosarcoma in the end as well. The experience taught me a lot about cancer treatments; I learned even more about potential cancer prevention.
This article briefly covers the most common cancers seen in dogs, how they develop, warning signs to watch for, conventional and holistic treatment options, and foods that may help support the body before, during, and after diagnosis.
Important note: Food and natural therapies do not cure cancer. They support the immune system, reduce inflammation, and improve quality of life, often alongside conventional veterinary care.
Hemangiosarcoma (HSA)
What it is
Hemangiosarcoma is an aggressive cancer of the blood vessels, most commonly affecting the spleen, heart, and liver. It often grows silently until a sudden rupture causes internal bleeding.
How it develops
Chronic inflammation
Oxidative stress
Immune dysregulation
Environmental toxins
Higher risk in senior dogs and certain breeds
This cancer is not contagious and often develops unnoticed.
Symptoms
Sudden weakness or collapse
Pale gums
Rapid breathing
Distended abdomen
Lethargy
Sudden death in severe cases
Common treatments
Conventional:
Emergency surgery (splenectomy)
Chemotherapy
Natural & integrative support:
Yunnan Baiyao (to help stop active bleeds)
Curcumin (turmeric)*
Antioxidants to reduce oxidative stress
*Curcumin (turmeric or golden paste) is often recommended for dogs with cancer; however, curcumin is an anti-clotting agent and isn’t recommended during an active bleed. This and other anti-clotting foods (garlic, fatty fish, leafy greens, broccoli) should be fed with care and under the guidance of a holistic veterinary oncologist or holistic vet.
Outcomes
Prognosis is often poor, but early detection + integrative care may improve quality of life and survival time.
Foods that support prevention & symptom management
Sardines, salmon (anti-inflammatory fats)*
Blueberries (antioxidants)
Dark leafy greens*
Bone broth (hydration + amino acids)
*Like curcumin, leafy greens, and fatty fish (sardines, salmon) have anti-clotting benefits and are not recommended to dogs with HSA during an active bleed.
Lymphoma (B-Cell and T-Cell)
What it is
Lymphoma is cancer of the lymphatic system, affecting lymph nodes, spleen, liver, and bone marrow.
B-cell lymphoma: more responsive to treatment
T-cell lymphoma: more aggressive
How it develops
Immune suppression
Chemical exposures (pesticides, herbicides)
Chronic inflammation
Possible viral and environmental triggers
Symptoms
Swollen lymph nodes
Weight loss
Loss of appetite
Fatigue
Increased thirst or urination
Common treatments
Conventional:
Chemotherapy (often effective short-term)
Steroids
Natural & integrative support:
Mushroom extracts (turkey tail, maitake)
Omega-3s to reduce inflammation
Probiotics for gut-immune balance
Detox support for liver health
Outcomes
Many dogs respond well initially. Diet and immune support may help extend remission and comfort.
Foods that support prevention & symptom management
Cruciferous vegetables (broccoli sprouts)
Fermented foods (gut health)
Pasture-raised eggs
Garlic (small, appropriate amounts)
Low-glycemic vegetables
Mast Cell Tumors (MCT)
What it is
Mast cell tumors arise from mast cells, which are part of the immune system and involved in allergic responses.
How it develops
Immune dysregulation
Chronic inflammation
Histamine imbalance
Genetics + environmental stressors
Symptoms
Lumps that change size
Redness or swelling
Vomiting or diarrhea
Stomach ulcers (from histamine release)
Common treatments
Conventional:
Surgical removal
Chemotherapy or radiation (for aggressive tumors)
Natural & integrative support:
Quercetin (natural antihistamine)
Anti-inflammatory herbs
Outcomes
Low-grade tumors often do very well with surgery. High-grade tumors require ongoing management.
Foods that support prevention & symptom management
Low-histamine proteins (fresh, properly stored meats)
Leafy greens
Blueberries
Omega-3 rich fish
Osteosarcoma
What it is
Osteosarcoma is an aggressive bone cancer, most commonly affecting large and giant breeds.
How it develops
Chronic inflammation
Oxidative damage
Poor mineral balance
Environmental stressors
Symptoms
Limping
Bone swelling
Pain
Fractures with minimal trauma
Common treatments
Conventional:
Amputation
Chemotherapy
Natural & integrative support:
Outcomes
Treatment can significantly improve comfort and extend life. Supportive care is critical.
Foods that support prevention & symptom management
Fatty fish
Anti-inflammatory herbs
Bone-supporting minerals from whole foods
Melanoma (Oral & Skin)
What it is
Melanoma arises from pigment-producing cells and is especially aggressive when found in the mouth.
How it develops
Immune suppression
Oxidative stress
Chronic inflammation
Environmental toxins
Symptoms
Oral masses
Bad breath
Bleeding gums
Facial swelling
Difficulty eating
Common treatments
Conventional:
Surgery
Radiation
Melanoma vaccine (in some cases)
Natural & integrative support:
Outcomes
Early detection greatly improves prognosis.
Foods that support prevention & symptom management
Blueberries
Leafy greens
Sardines
Soft, nutrient-dense foods during treatment
A Note on Prevention
While no diet can guarantee cancer prevention, reducing inflammation and immune stress matters.
Supportive daily strategies:
Feed fresh, whole foods
Avoid ultra-processed diets when possible
Reduce toxin exposure (lawns, cleaners, plastics)
Support gut health
Introduce functional mushrooms into the diet
Encourage movement and mental enrichment
My Thoughts on Canine Cancer
Cancer is scary—but knowledge is power. Supporting your dog with better nutrition, reduced toxin load, and immune-supportive foods may help lower risk, improve outcomes, and enhance quality of life.
I haven’t found the magical regimen to avoid cancer, I’m applying what I’ve learned to my dogs, praying that they remain cancer-free. Besides feeding a raw and gently cooked fresh food diet, I follow the above-listed “supportive daily strategies,” and add the following supplements to their diet as needed:
Daily Dawg, Real Mushrooms (alternating with Turkey Tail and 5 Defenders)
Gussy’s Gut (alternating between Boost, Sustain, and Youthful Grasses & Sprouts)
CBD Oil, Earth Buddy Pet (cellular support)
Maxx Life, Earth Buddy Pet (glutathione & liver support)
Pawsitive Immunity, Adored Beast (a gut supporting product without histamines for Buffy)
Vital Defense, Adored Beast (cellular support)
I wish I had the answers, but I don’t, so I stay open to new information, praying that I find the answer, the diet, the supplement, the regimen that will help me raise happier, healthier dogs.
If you’re interested in learning more about canine cancer, check out this course offered by Dr. Kendra Pope: Pet Cancer Prevention Course
