Glutathione: Why It Matters for Dogs
Glutathione is often called the “master antioxidant” because it helps the body detox, supports liver function, boosts the immune system, and protects cells from oxidative stress (which accelerates aging). For senior dogs, allergy dogs, cancer-prone dogs, and dogs dealing with chronic inflammation, glutathione can make a noticeable difference in energy, recovery, and overall vitality.
Benefits:
Supports liver detox pathways
Helps reduce inflammation
Protects cells from free-radical damage
Supports cognitive and immune health
Risks:
Most dogs tolerate glutathione very well. The only real “risk” is giving too much. High doses can cause mild digestive upset in sensitive dogs — think soft stool or gurgly belly — but this is rare and usually dose-related.
What About Antioxidant-Rich Foods?
Blueberries and other antioxidant-rich foods (spinach, kale, broccoli sprouts, cranberries, etc.), but they work differently than glutathione. Antioxidant foods provide dietary antioxidants that help reduce inflammation and support overall health.
Glutathione, however, is the body’s master antioxidant — the one cells use to detoxify, repair damage, and protect the liver, brain, and immune system. Dogs naturally lose glutathione as they age, and chronic issues (allergies, inflammation, toxins) use it up even faster.
Think of it this way:
Blueberries = helpful antioxidants
Glutathione = the antioxidant your dog’s cells run on
Both are beneficial, but blueberries and broccoli sprouts can’t replace glutathione — they work best together to support long-term health.
My Go-To Products:
Maxx Life (Earth Buddy Pet) — ideal for senior dogs or dogs with chronic conditions that drain antioxidant reserves.
Liposomal Glutathione (Earth Buddy Pet) — the liposomal format allows for better absorption and is perfect for dogs needing a fast, effective antioxidant boost.
If your dog needs ongoing antioxidant support, glutathione is one of the most effective tools we have.
2. Why a Base Mix + Meat Isn’t Automatically “Balanced”
Base mixes are amazing tools — I use a homemade version myself — but mixing them with only a single protein isn’t guaranteed to meet your dog’s full nutritional needs. That’s because:
Most base mixes are designed to complete a recipe, not create one.
Vitamins and minerals shift when you change proteins (for example, some meats are low in zinc, manganese, or copper).
Calcium, phosphorus, and trace minerals vary widely depending on fat %, organ %, and bone %.
This means your dog might get a near-balanced meal… or they might miss important nutrients like iodine, vitamin D, manganese, and omega-3s.
What to Use Instead:
I always recommend the Animal Diet Formulator (ADF) software because it calculates every nutrient in your recipe — protein, fat, minerals, vitamins, amino acids — and shows you exactly what’s missing. I began using the software to tweak my recipes, making sure I was covering all the nutritional bases for my dogs. A base mix is a good start, but ADF gets you over the finish line.
Balanced meals = fewer health problems later.
Getting Past the Price Tag:
This software isn’t cheap, but there are ways to get around it. Take advantage of the less expensive two-week trial offer or sign up for $25/month for a brief period.
3. Functional Mushrooms: Why Twice Daily Is Better
Functional mushrooms — like reishi, lion’s mane, turkey tail, cordyceps, and chaga — don’t last in the body very long. Their active compounds (beta-glucans, terpenes, and antioxidants) are used quickly, and blood levels start dropping around the 10–12 hour mark.
That means feeding them once daily gives your dog a half day of support… and a half day of nothing.
Feeding functional mushrooms twice daily keeps your dog’s immune system, gut, brain, and inflammatory pathways supported around the clock. This is especially important for:
senior dogs
allergy dogs
dogs with joint issues
cancer-prone breeds
highly active dogs
Small amounts, twice a day, = better absorption, better consistency, and better results.
My Go-To Products (Functional Mushrooms)
Daily Dawg (Real Mushrooms) — A great everyday mushroom blend for overall immune support, gut health, and general wellness.
5 Defenders (Real Mushrooms) — A powerhouse blend ideal for senior dogs, cancer-prone dogs, dogs with chronic inflammation, or pups needing stronger immune system support.
Clarity (MycoDog) — Focused on brain and nervous system health — great for senior dogs, dogs with cognitive decline, anxious dogs, or any dog who needs better focus and mental clarity.
Allergy & Immune Support (Woof Creek) — Designed for dogs dealing with environmental or food-related allergies, seasonal itching, gut issues, or ongoing immune imbalance.
Read More: Functional Mushrooms for Dogs
4. Feeding Once Daily vs. Feeding in a 6–7 Hour Window
For years, I’ve heard that feeding dogs once a day is “optimal,” but that never made sense for my crew. It’s too much food at once for my dogs, and several supplements — like functional mushrooms — only last about 12 hours. So feeding twice daily, but within a 6–7 hour window (intermittent fasting), works best for us.
Why Time-Restricted Feeding Helps:
Feeding dogs within a shorter daily eating window (like 6–7 hours) supports:
Better digestion: The gut gets time to rest and repair instead of staying in “work mode” all day.
More stable blood sugar: Less grazing = fewer insulin spikes.
Consistent supplement absorption: Especially important for antioxidants, mushrooms, and herbs.
Metabolic health: Research suggests that time-restricted feeding supports weight control, energy balance, and longevity pathways.
You can absolutely feed twice — just cluster meals within a shorter window to mimic natural eating patterns and support better metabolic health.
5. Collagen: Why Dogs Need It and the Best Sources
Collagen is the protein that supports joints, skin, coat, nails, gut lining, and connective tissue. Dogs naturally lose collagen as they age — just like we do — which can lead to stiffness, dry skin, weaker nails, and slower recovery.
Benefits of Collagen:
Supports joint lubrication and mobility, and bone density as a dog ages
Helps repair and maintain a healthy gut lining; improves digestion
Improves skin hydration and coat quality
Strengthens nails and connective tissue
Boosts healing and recovery
Helps promote cognitive health by supporting healthy blood vessels
Best Food Sources of Collagen: Bone Broth & Real Dog Box
Bone broth — gentle, easy to digest, great for seniors or sensitive dogs (avoid or limit if your dog has allergies due to the high histamine levels)
Pig or cow skin — very high in collagen
Beef or bison trachea — naturally rich in collagen + glucosamine
Beef backstrap / tendons — great chew option with concentrated collagen
Each source has different strengths:
Bone broth = best for digestion and hydration
Skin = highest collagen density
Trachea = collagen plus natural joint-supporting compounds
Backstrap/tendons = long-lasting chews that also support dental health
A mix of these gives your dog the full spectrum of collagen benefits.
You may have noticed that this is a different format from the one I usually use - a deep dive on one topic. I couldn’t settle on one subject, so I decided to cover several today. Next week is the first Sunday of December, which means I’ll be sharing a recipe. If there’s a protein that you’d like me to focus on, let me know.
Disclaimer
I’m not a veterinarian or a practicing professional canine nutritionist. The Raw Feeder Life newsletter is simply a place where I share what I’m learning about canine nutrition and holistic pet health — the wins, the tools, and the things that are helping my own dogs thrive. My goal is to give you ideas, not prescriptions.
Every dog is different, and what works for mine may not be the perfect fit for yours. Please do your homework, talk to your trusted professionals when needed, and always focus on the dog(s) in front of you.
Myth: Pet insurance doesn’t cover everything
Many pet owners worry that insurance won’t cover everything, especially routine care or pre-existing conditions. While that’s true in many cases, most insurers now offer wellness add-ons for preventive care like vaccines, dental cleanings, and check-ups, giving you more complete coverage. View Money’s pet insurance list to find plans for as low as $10 a month.

